Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos |
| Phenotype | phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos |
| Upregulated in class | wtNotch |
| GeneSet | INOH_CANONICAL NOTCH SIGNALING PATHWAY |
| Enrichment Score (ES) | -0.89296037 |
| Normalized Enrichment Score (NES) | -1.7527769 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.025632232 |
| FWER p-Value | 0.101 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CREBBP | 5690035 7040050 | 1349 | 0.214 | -0.0527 | No | ||
| 2 | MAML1 | 2760008 | 1452 | 0.193 | -0.0403 | No | ||
| 3 | LFNG | 5360711 | 2283 | 0.103 | -0.0754 | No | ||
| 4 | ADAM17 | 360292 | 2989 | 0.061 | -0.1076 | No | ||
| 5 | MFNG | 1770242 4280348 | 3615 | 0.039 | -0.1376 | No | ||
| 6 | FURIN | 4120168 | 3692 | 0.037 | -0.1382 | No | ||
| 7 | DLL1 | 1770377 | 4165 | 0.028 | -0.1610 | No | ||
| 8 | RBPJ | 2360164 5550136 5720402 | 4423 | 0.024 | -0.1726 | No | ||
| 9 | NUMB | 2450735 3800253 6350040 | 5338 | 0.015 | -0.2204 | No | ||
| 10 | JAG2 | 1500341 | 6990 | 0.007 | -0.3086 | No | ||
| 11 | JAG1 | 3440390 | 7728 | 0.004 | -0.3478 | No | ||
| 12 | ADAM10 | 3780156 | 8265 | 0.003 | -0.3764 | No | ||
| 13 | DLL3 | 4010093 | 8793 | 0.001 | -0.4046 | No | ||
| 14 | DLL4 | 6400403 | 10357 | -0.003 | -0.4884 | No | ||
| 15 | NOTCH2 | 2570397 | 13080 | -0.014 | -0.6335 | No | ||
| 16 | PSEN2 | 130382 | 14767 | -0.035 | -0.7210 | No | ||
| 17 | FBXW7 | 4210338 7050280 | 14811 | -0.035 | -0.7200 | No | ||
| 18 | RFNG | 6290086 | 15174 | -0.045 | -0.7353 | No | ||
| 19 | NOTCH4 | 2450040 6370707 | 15203 | -0.046 | -0.7326 | No | ||
| 20 | ITCH | 1410731 5700022 | 15220 | -0.046 | -0.7291 | No | ||
| 21 | DTX3 | 1690458 | 18267 | -0.549 | -0.8420 | Yes | ||
| 22 | DTX2 | 4210041 7000008 | 18412 | -0.747 | -0.7804 | Yes | ||
| 23 | NOTCH3 | 3060603 | 18554 | -1.615 | -0.6382 | Yes | ||
| 24 | PSEN1 | 130403 2030647 6100603 | 18571 | -1.789 | -0.4731 | Yes | ||
| 25 | NOTCH1 | 3390114 | 18588 | -2.330 | -0.2577 | Yes | ||
| 26 | DTX1 | 5900372 | 18597 | -2.793 | 0.0010 | Yes |
